Disentangling the influence of reservoir abundance and pathogen shedding on zoonotic spillover of the Leptospira agent in urban informal settlements

• Main Authors: Nirali Soni (Author), Max T. Eyre (Author), Fábio N. Souza (Author), Peter J. Diggle (Author), Albert I. Ko (Author), Mike Begon (Author), Roger Pickup (Author), James E. Childs (Author), Hussein Khalil (Author), Ticiana S. A. Carvalho-Pereira (Author), Arsinoê C. Pertile (Author), Mayara Carvalho (Author), Daiana de Oliveira (Author), Nivison Nery (Author), Emanuele Giorgi (Author), Federico Costa (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rats are major reservoirs for pathogenic Leptospira, the bacteria causing leptospirosis, particularly in urban informal settlements. However, the impact of variation in rat abundance and pathogen shedding rates on spillover transmission to humans remains unclear. This study aimed to investigate how...