Evaluation of drug-drug interaction between rilpivirine and rifapentine using PBPK modelling

Tuberculosis remains the leading cause of death among people living with HIV. Rifapentine is increasingly used to treat active disease or prevent reactivation, in both cases given either as weekly or daily therapy. However, rifapentine is an inducer of CYP3A4, potentially interacting with antiretrov...

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Main Authors: Sandra Grañana-Castillo (Author), Maiara Camotti Montanha (Author), Rachel Bearon (Author), Saye Khoo (Author), Marco Siccardi (Author)
Format: Book
Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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