Increased humoral immunity by DNA vaccination using an α-tocopherol-based adjuvant

• Main Authors: Ingrid Karlsson (Author), Marie Borggren (Author), Jens Nielsen (Author), Dennis Christensen (Author), Jim Williams (Author), Anders Fomsgaard (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

DNA vaccines induce broad immunity, which involves both humoral and strong cellular immunity, and can be rapidly designed for novel or evolving pathogens such as influenza. However, the humoral immunogenicity in humans and higher animals has been suboptimal compared with that of traditional vaccine...