Design and characterization of glimepiride hydrotropic solid dispersion to enhance the solubility and dissolution

• Main Authors: Devakamma Lakumalla (Author), Neeraja Podichety (Author), Ravikumar Maddali (Author)
• Formato: Livro
• Publicado em: Creative Pharma Assent, 2024-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Glimepiride lowers blood sugar levels in the body, and treats type 2 diabetes mellitus. But the main problem with the drug is its low aqueous solubility. The primary purpose of this study is to increase its solubility in an aqueous medium by using amphiphilic hydrotropic agents instead o...