CpG Island Methylation in Sessile Serrated Adenoma/Polyp of the Colorectum: Implications for Differential Diagnosis of Molecularly High-Risk Lesions among Non-dysplastic Sessile Serrated Adenomas/Polyps

• Main Authors: Ji Ae Lee (Author), Hye Eun Park (Author), Seung-Yeon Yoo (Author), Seorin Jeong (Author), Nam-Yun Cho (Author), Gyeong Hoon Kang (Author), Jung Ho Kim (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Although colorectal sessile serrated adenomas/polyps (SSA/Ps) with morphologic dysplasia are regarded as definite high-risk premalignant lesions, no reliable grading or risk-stratifying system exists for non-dysplastic SSA/Ps. The accumulation of CpG island methylation is a molecular hall...