Upregulation of TCPTP in Macrophages Is Involved in IL-35 Mediated Attenuation of Experimental Colitis

• Main Authors: Baoren Zhang (Author), Chenglu Sun (Author), Yanglin Zhu (Author), Hong Qin (Author), Dejun Kong (Author), Jingyi Zhang (Author), Bo Shao (Author), Xiang Li (Author), Shaohua Ren (Author), Hongda Wang (Author), Jingpeng Hao (Author), Hao Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ulcerative colitis (UC) is a chronic intestinal inflammatory disease with complex etiology. Interleukin-35 (IL-35), as a cytokine with immunomodulatory function, has been shown to have therapeutic effects on UC, but its mechanism is not yet clear. Therefore, we constructed Pichia pastoris stably exp...