CK2 Molecular Targeting-Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer

• Main Authors: Janeen H. Trembley (Author), Betsy T. Kren (Author), Md. Joynal Abedin (Author), Rachel I. Vogel (Author), Claire M. Cannon (Author), Gretchen M. Unger (Author), Khalil Ahmed (Author)
• Format: Book
• Published: MDPI AG, 2017-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein kinase CK2 demonstrates increased protein expression relative to non-transformed cells in the majority of cancers that have been examined. The elevated levels of CK2 are involved in promoting not only continued proliferation of cancer cells but also their resistance to cell death; thus, CK2...