Sanguinarine inhibits melanoma invasion and migration by targeting the FAK/PI3K/AKT/mTOR signalling pathway

• Main Authors: Xiaoyi Qi (Author), Yonglan Chen (Author), Sha Liu (Author), Li Liu (Author), Zehui Yu (Author), Ling Yin (Author), Lu Fu (Author), Mingming Deng (Author), Sicheng Liang (Author), Muhan Lü (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext Sanguinarine (SAG) is the most abundant constituent of Macleaya cordata (Willd.) R. Br. (Popaceae). SAG has shown antimammary and colorectal metastatic effects in mice in vivo, suggesting its potential for cancer chemotherapy.Objective To determine the antimetastatic effect and under...