Expanding the horizons of targeted protein degradation: A non-small molecule perspective

• Main Authors: Xiaowei Huang (Author), Fengbo Wu (Author), Jing Ye (Author), Lian Wang (Author), Xiaoyun Wang (Author), Xiang Li (Author), Gu He (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Targeted protein degradation (TPD) represented by proteolysis targeting chimeras (PROTACs) marks a significant stride in drug discovery. A plethora of innovative technologies inspired by PROTAC have not only revolutionized the landscape of TPD but have the potential to unlock functionalities beyond...