Expanding the horizons of targeted protein degradation: A non-small molecule perspective

• المؤلفون الرئيسيون: Xiaowei Huang (مؤلف), Fengbo Wu (مؤلف), Jing Ye (مؤلف), Lian Wang (مؤلف), Xiaoyun Wang (مؤلف), Xiang Li (مؤلف), Gu He (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2024-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Targeted protein degradation (TPD) represented by proteolysis targeting chimeras (PROTACs) marks a significant stride in drug discovery. A plethora of innovative technologies inspired by PROTAC have not only revolutionized the landscape of TPD but have the potential to unlock functionalities beyond...