Expanding the horizons of targeted protein degradation: A non-small molecule perspective

• मुख्य लेखकों: Xiaowei Huang (लेखक), Fengbo Wu (लेखक), Jing Ye (लेखक), Lian Wang (लेखक), Xiaoyun Wang (लेखक), Xiang Li (लेखक), Gu He (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2024-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Targeted protein degradation (TPD) represented by proteolysis targeting chimeras (PROTACs) marks a significant stride in drug discovery. A plethora of innovative technologies inspired by PROTAC have not only revolutionized the landscape of TPD but have the potential to unlock functionalities beyond...