The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels

Pulmonary arterial hypertension (PAH) is an aggressive vascular remodeling disease that carries a high morbidity and mortality rate. Treprostinil (Remodulin) is a stable prostacyclin analogue with potent vasodilatory and anti-proliferative activity, approved by the FDA and WHO as a treatment for PAH...

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Bibliographic Details
Main Authors: Kevin P. Cunningham (Author), Lucie H. Clapp (Author), Alistair Mathie (Author), Emma L. Veale (Author)
Format: Book
Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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