Novel decoy cellular vaccine strategy utilizing transgenic antigen-expressing cells as immune presenter and adjuvant in vaccine prototype against SARS-CoV-2 virus

• Main Authors: Henry Ji (Author), Ying Yan (Author), Beibei Ding (Author), Wenzhong Guo (Author), Mark Brunswick (Author), Andreas Niethammer (Author), Williams SooHoo (Author), Robin Smith (Author), Alexis Nahama (Author), Yanliang Zhang (Author)
• Format: Book
• Published: Elsevier, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A novel approach modifying cells to express viral markers to elicit protective immunity responses (decoy cellular vaccination) in the prevention of COVID-19 disease is currently being explored. Our approach entails utilizing SARS-CoV-2 Spike antigen-expressing, non-replicating cells as carriers and...