Demeanor of rivaroxaban in activated/inactivated FXa

• Main Authors: Kaname Seki (Author), Yosuke Mizuno (Author), Toku Sakashita (Author), Shintaro Nakano (Author), Jun Tanno (Author), Yasushi Okazaki (Author), Toshihiro Muramatsu (Author), Shigeyuki Nishimura (Author), Takaaki Senbonmatsu (Author)
• Format: Book
• Published: Elsevier, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Activated factor X (FXa) plays an important role in thrombin generation and inflammation. Factor X is not converted constitutively to FXa, but only after intrinsic clotting factors are activated and/or cellular injury occurs. Although rivaroxaban is one of direct FXa inhibitors, its function in the...