Synergy of Omeprazole and Praziquantel In Vitro Treatment against Schistosoma mansoni Adult Worms.

• Main Authors: Giulliana T Almeida (Author), Regina C G Lage (Author), Leticia Anderson (Author), Thiago M Venancio (Author), Helder I Nakaya (Author), Patrícia A Miyasato (Author), Henrique K Rofatto (Author), Adhemar Zerlotini (Author), Eliana Nakano (Author), Guilherme Oliveira (Author), Sergio Verjovski-Almeida (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel (PZQ), and the selection of resistant worms under repeated treatment is a concern. Therefore, there is a pressing need to understand the molecular effects of PZQ on schistosomes and to investigate alternative or...