Disialoganglioside GD2-Targeted Near-Infrared Photoimmunotherapy (NIR-PIT) in Tumors of Neuroectodermal Origin

• Главные авторы: Fuyuki F. Inagaki (Автор), Takuya Kato (Автор), Aki Furusawa (Автор), Ryuhei Okada (Автор), Hiroaki Wakiyama (Автор), Hideyuki Furumoto (Автор), Shuhei Okuyama (Автор), Peter L. Choyke (Автор), Hisataka Kobayashi (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2022-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Disialoganglioside (GD2) is a subtype of glycolipids that is highly expressed in tumors of neuroectodermal origins, such as neuroblastoma and osteosarcoma. Its limited expression in normal tissues makes GD2 a potential target for precision therapy. Several anti-GD2 monoclonal antibodies are currentl...