Disialoganglioside GD2-Targeted Near-Infrared Photoimmunotherapy (NIR-PIT) in Tumors of Neuroectodermal Origin

• Main Authors: Fuyuki F. Inagaki (Author), Takuya Kato (Author), Aki Furusawa (Author), Ryuhei Okada (Author), Hiroaki Wakiyama (Author), Hideyuki Furumoto (Author), Shuhei Okuyama (Author), Peter L. Choyke (Author), Hisataka Kobayashi (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Disialoganglioside (GD2) is a subtype of glycolipids that is highly expressed in tumors of neuroectodermal origins, such as neuroblastoma and osteosarcoma. Its limited expression in normal tissues makes GD2 a potential target for precision therapy. Several anti-GD2 monoclonal antibodies are currentl...