Does Proteosome Inhibition Decrease or Accelerate Toxin-Induced Dopaminergic Neurodegeneration?

• Κύριοι συγγραφείς: Rieko Setsuie (Συγγραφέας), Tomohiro Kabuta (Συγγραφέας), Keiji Wada (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2005-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Parkinson's disease (PD) is pathologically characterized by dopaminergic (DA) cell death and the presence of Lewy bodies (LB) in the brain. α-Synuclein (α-syn) and ubiquitin (Ub) are the major components of LB, however, the process of their accumulation and their relationship to DA cell loss ha...