Oxidative Damage Induced by Phototoxic Pheophorbide a 17-Diethylene Glycol Ester Encapsulated in PLGA Nanoparticles

• Asıl Yazarlar: Mariia R. Mollaeva (Yazar), Elena Nikolskaya (Yazar), Veronika Beganovskaya (Yazar), Maria Sokol (Yazar), Margarita Chirkina (Yazar), Sergey Obydennyi (Yazar), Dmitry Belykh (Yazar), Olga Startseva (Yazar), Murad D. Mollaev (Yazar), Nikita Yabbarov (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Pheophorbide a 17-diethylene glycol ester (XL-8), is a promising high-active derivative of known photosensitizer chlorin e6 used in photodynamic therapy. However, high lipophilicity and poor tumor accumulation limit XL-8 therapeutic application. We developed a novel XL-8 loaded with poly(D,L-lactide...