IL-33/ST2 Pathway and Classical Cytokines in End-Stage Heart Failure Patients Submitted to Left Ventricular Assist Device Support: A Paradoxic Role for Inflammatory Mediators?

• Main Authors: C. Caselli (Author), A. D'Amico (Author), R. Ragusa (Author), R. Caruso (Author), T. Prescimone (Author), M. Cabiati (Author), S. Nonini (Author), P. Marraccini (Author), S. Del Ry (Author), M. G. Trivella (Author), O. Parodi (Author), D. Giannessi (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Inflammation is a critical process contributing to heart failure (HF). We hypothesized that IL-33/ST2 pathway, a new mechanism regulated during cardiac stress, may be involved in the functional worsening of end-stage HF patients, candidates for left ventricular assist device (LVAD) impla...