Enhanced Detection of Desmoplasia by Targeted Delivery of Iron Oxide Nanoparticles to the Tumour-Specific Extracellular Matrix

• Main Authors: Meenu Chopra (Author), Jiansha Wu (Author), Yen Ling Yeow (Author), Louise Winteringham (Author), Tristan D. Clemons (Author), Martin Saunders (Author), Venkata Ramana Kotamraju (Author), Ruth Ganss (Author), Kirk W. Feindel (Author), Juliana Hamzah (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diagnostic imaging of aggressive cancer with a high stroma content may benefit from the use of imaging contrast agents targeted with peptides that have high binding affinity to the extracellular matrix (ECM). In this study, we report the use of superparamagnetic iron-oxide nanoparticles (IO-NP) conj...