Validated stability indicating methods for determination of nitazoxanide in presence of its degradation products

• Main Authors: Nouruddin W. Ali (Author), Samah Sayed Abbas (Author), Hala El-Sayed Zaazaa (Author), Maha Mohamed Abdelrahman (Author), Mohamed Abdelkawy (Author)
• Format: Book
• Published: Elsevier, 2012-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Three sensitive, selective and reproducible stability-indicating methods are presented for determination of nitazoxanide (NTZ), a new anti-protozoal drug, in presence of its degradation products. Method A utilizes the first derivative of ratio spectra spectrophotometry by measurement of the amplitud...