Chemotherapy‐induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol

• Main Authors: Daniel I. Brierley (Author), Joe R. Harman (Author), Natasha Giallourou (Author), Emma Leishman (Author), Anna Emily Roashan (Author), Ben A.D. Mellows (Author), Heather B. Bradshaw (Author), Jonathan R. Swann (Author), Ketan Patel (Author), Benjamin J. Whalley (Author), Claire M. Williams (Author)
• Format: Book
• Published: Wiley, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Muscle wasting, anorexia, and metabolic dysregulation are common side‐effects of cytotoxic chemotherapy, having a dose‐limiting effect on treatment efficacy, and compromising quality of life and mortality. Extracts of Cannabis sativa, and analogues of the major phytocannabinoid Δ...