Rapamycin treatment induces tubular proteinuria: role of megalin-mediated protein reabsorption
Introduction: Rapamycin is an immunosuppressor that acts by inhibiting the serine/threonine kinase mechanistic target of rapamycin complex 1. Therapeutic use of rapamycin is limited by its adverse effects. Proteinuria is an important marker of kidney damage and a risk factor for kidney diseases prog...
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Main Authors: | Rodrigo A. S. Peres (Author), Diogo B. Peruchetti (Author), Rodrigo P. Silva-Aguiar (Author), Douglas E. Teixeira (Author), Carlos P. Gomes (Author), Christina M. Takiya (Author), Ana Acacia S. Pinheiro (Author), Celso Caruso-Neves (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2023-07-01T00:00:00Z.
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