Computational Design of Inhibitors Targeting the Catalytic β Subunit of <i>Escherichia coli</i> F_OF₁-ATP Synthase

• Päätekijät: Luis Pablo Avila-Barrientos (Tekijä), Luis Fernando Cofas-Vargas (Tekijä), Guillermin Agüero-Chapin (Tekijä), Enrique Hernández-García (Tekijä), Sergio Ruiz-Carmona (Tekijä), Norma A. Valdez-Cruz (Tekijä), Mauricio Trujillo-Roldán (Tekijä), Joachim Weber (Tekijä), Yasser B. Ruiz-Blanco (Tekijä), Xavier Barril (Tekijä), Enrique García-Hernández (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

With the uncontrolled growth of multidrug-resistant bacteria, there is an urgent need to search for new therapeutic targets, to develop drugs with novel modes of bactericidal action. FoF1-ATP synthase plays a crucial role in bacterial bioenergetic processes, and it has emerged as an attractive antim...