Ex vivo Stimulatory Capacity of TLR3 and TLR4 is reduced in HIV-Infected Rapid Progressors and Enhanced Long-Term Non-Progressors

• Main Author: Steven E. Bosinger,1,2 Prameet M. Sheth,3 Ali Danesh,2,4 Leonard Noay,5 Roberta Halpenny,5 Shari Gordon,6,7,8 Silvija Staprans,7,8 Guido Silvestri,6 Colin Kovacs,5 Rupert Kaul,3 and David J. Kelvin.2,4 (Author)
• Format: Book
• Published: The Journal of Infection in Developing Countries, 2007-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Toll-like receptors (TLRs) may be important in the ability of host innate immunity to control HIV infection. To investigate TLR activity in association with HIV disease, we examined the compared the ex vivo stimulatory capacity of TLRs in patients with chronic, asymptomatic HIV infection...