Aloperine Protects Mice against DSS-Induced Colitis by PP2A-Mediated PI3K/Akt/mTOR Signaling Suppression

• Main Authors: Xiaoxia Fu (Author), Fei Sun (Author), Faxi Wang (Author), Junai Zhang (Author), Biying Zheng (Author), Jixin Zhong (Author), Tiantian Yue (Author), Xuebao Zheng (Author), Jun-Fa Xu (Author), Cong-Yi Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colitis is a major form of inflammatory bowel disease which involved mucosal immune dysfunction. Aloperine is an alkaloid isolated from the shrub Sophora alopecuroides L. and has been recognized as an effective treatment for inflammatory and allergic diseases. The present study aimed to examine the...