Porous Nanostructure, Lipid Composition, and Degree of Drug Supersaturation Modulate In Vitro Fenofibrate Solubilization in Silica-Lipid Hybrids

The unique nanostructured matrix obtained by silica-lipid hybrids (SLHs) is well known to improve the dissolution, absorption, and bioavailability of poorly water-soluble drugs (PWSDs). The aim of this study was to investigate the impact of: (i) drug load: 3-22.7% <i>w/w</i>, (ii) lipid...

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Main Authors: Ruba Almasri (Author), Paul Joyce (Author), Hayley B. Schultz (Author), Nicky Thomas (Author), Kristen E. Bremmell (Author), Clive A. Prestidge (Author)
Format: Book
Published: MDPI AG, 2020-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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