Effects of tumour necrosis factor-α on BrdU incorporation in cultured human enterocytes

• Main Authors: J. McDevitt (Author), C. Feighery (Author), C. O'Farrelly (Author), G. Martin (Author), D. G. Weir (Author), D. Kelleher (Author)
• Format: Book
• Published: Hindawi Limited, 1995-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bromodeoxyuridine incorporation is a useful method for studying the pattern of DNA synthesis in proliferating cells. The distribution pattern of incorporated BrdU in villus enterocytes of duodenal explants was analysed after exposure to TNFα in organ culture. TNFα caused a consistent, low level upta...