Pharmacokinetic/pharmacodynamic modeling of drug interactions at the P2Y12 receptor between selatogrel and oral P2Y12 antagonists

• Main Authors: Andrea Henrich (Author), Christian Hove Claussen (Author), Jasper Dingemanse (Author), Andreas Krause (Author)
• Format: Knjiga
• Izdano: Wiley, 2021-07-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract Selatogrel is a potent and reversible P2Y12 receptor antagonist developed for subcutaneous self‐administration by patients with suspected acute myocardial infarction. After single‐dose emergency treatment with selatogrel, patients are switched to long‐term treatment with oral P2Y12 receptor...