Oral administration of crocin-loaded solid lipid nanoparticles inhibits neuroinflammation in a rat model of epileptic seizures by activating SIRT1 expression

• Main Authors: Seyran Kakebaraei (Author), Mohammadreza Gholami (Author), Touraj Zamir Nasta (Author), Elham Arkan (Author), Fariborz Bahrehmand (Author), Sajad Fakhri (Author), Cyrus Jalili (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and purpose: Epilepsy is a group of chronic neurological diseases caused by a complex set of neuronal hyper electrical activities and oxidative stress of neurons. Crocin is a natural bioactive agent of saffron with different pharmacological properties and low bioavailability. This study a...