Digoxin Enhances the Anticancer Effect on Non-Small Cell Lung Cancer While Reducing the Cardiotoxicity of Adriamycin

• Main Authors: Yingying Wang (Author), Qian Ma (Author), Shaolu Zhang (Author), Hongyan Liu (Author), Baoquan Zhao (Author), Bo Du (Author), Wei Wang (Author), Peng Lin (Author), Zhe Zhang (Author), Yuxu Zhong (Author), Dexin Kong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Digoxin is widely used to treat heart failure. Epidemiological studies suggested it might be used as an anticancer drug or sensitizing agent for cancer therapy. Adriamycin is a well-known anticancer drug, but often causes cardiotoxicity which limits its use. We recently investigated the anticancer e...