Spautin-1 Ameliorates Acute Pancreatitis via inhibiting impaired Autophagy and Alleviating Calcium Overload

• Main Authors: Juan Xiao (Author), Xueping Feng (Author), Xiao-Ying Huang (Author), Zhongshi Huang (Author), Yanqiang Huang (Author), Chaogan Li (Author), Genliang Li (Author), Song Nong (Author), Ruoshi Wu (Author), Yongzhi Huang (Author), Xi-Dai Long (Author)
• Format: Book
• Published: BMC, 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Acute pancreatitis is characterized by zymogen preactivation. Severe inflammation caused by zymogen activation can eventually lead to multiple organ dysfunctions which contribute to the high mortality rate of severe acute pancreatitis. However, there is no specific treatment available for a...