Evidence for inefficient contraction and abnormal mitochondrial activity in sarcopenia using magnetic resonance spectroscopy

• Main Authors: Mary C. Stephenson (Author), Jamie X.M. Ho (Author), Eugenia Migliavacca (Author), Maria Kalimeri (Author), Neerja Karnani (Author), Subhasis Banerji (Author), John J. Totman (Author), Jerome N. Feige (Author), Reshma A. Merchant (Author), Stacey K.H. Tay (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mitochondrial dysfunction has been implicated in sarcopenia. 31P magnetic resonance spectroscopy (MRS) enables non‐invasive measurement of adenosine triphosphate (ATP) synthesis rates to probe mitochondrial function. Here, we assessed muscle energetics in older sarcopenic and non...