Variable in Vivo and in Vitro Biological Effects of Cerium Oxide Nanoparticle Formulations

• Main Authors: Karin L. Heckman (Author), Ana Y. Estevez (Author), William DeCoteau (Author), Stephanie Vangellow (Author), Samantha Ribeiro (Author), Joseph Chiarenzelli (Author), Bonnie Hays-Erlichman (Author), Joseph S. Erlichman (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cerium oxide nanoparticles (CeNPs) exhibit redox capacity in vitro with efficacy in in vivo disease models of oxidative stress. Here we compare, in parallel, three CeNP formulations with distinct chemical stabilizers and size. In vitro assays revealed antioxidant activity from all the CeNPs, but whe...