Response to olaparib in metastatic castration-resistant prostate cancer with germline BRCA2 mutation: a case report

• Main Authors: Yi Ma (Author), Lijie He (Author), Qianwen Huang (Author), Shuang Zheng (Author), Zhiqiang Zhang (Author), Hongshi Li (Author), Shuang Liu (Author)
• Format: Book
• Published: BMC, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Prostate cancer is a heterogeneous disease, meaning patients would benefit from different treatment strategies based on their molecular stratification. In recent years, several genomic studies have identified prostate cancers with defects in DNA repair genes. It is known that the...