Exposure to Toxic Heavy Metals Can Influence Homocysteine Metabolism?

• Main Authors: Caterina Ledda (Author), Emanuele Cannizzaro (Author), Piero Lovreglio (Author), Ermanno Vitale (Author), Angela Stufano (Author), Angelo Montana (Author), Giovanni Li Volti (Author), Venerando Rapisarda (Author)
• Format: Book
• Published: MDPI AG, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Homocysteine is a sulfur amino acid whose metabolism is activated in two pathways: remethylation to methionine, which requires folate and vitamin B₁₂, and transsulfuration to cystathionine, which needs pyridoxal-5’-phosphate. High homocysteine level incre...