Self-attention enabled deep learning of dihydrouridine (D) modification on mRNAs unveiled a distinct sequence signature from tRNAs

Dihydrouridine (D) is a modified pyrimidine nucleotide universally found in viral, prokaryotic, and eukaryotic species. It serves as a metabolic modulator for various pathological conditions, and its elevated levels in tumors are associated with a series of cancers. Precise identification of D sites...

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Main Authors: Yue Wang (Author), Xuan Wang (Author), Xiaodong Cui (Author), Jia Meng (Author), Rong Rong (Author)
Format: Book
Published: Elsevier, 2023-03-01T00:00:00Z.
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