Comparison of conventional and supported liquid extraction methods for the determination of sitagliptin and simvastatin in rat plasma by LCâESIâMS/MS

• Main Authors: B. Ramesh (Author), N. Manjula (Author), S.R. Bijargi (Author), V.U.M. Sarma (Author), P. Sita Devi (Author)
• Format: Book
• Published: Elsevier, 2015-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Three extraction methods were compared for their efficiency to analyze sitagliptin and simvastatin in rat plasma by LCâMS/MS, including (1) liquidâliquid extraction (LLE), (2) solid phase extraction (SPE) and (3) supported liquid extraction (SLE). Comparison of recoveries of analytes with different...