Effects of Brain-Derived Neurotrophic Factor on Local Inflammation in Experimental Stroke of Rat

• Main Authors: Yongjun Jiang (Author), Ning Wei (Author), Juehua Zhu (Author), Tingting Lu (Author), Zhaoyao Chen (Author), Gelin Xu (Author), Xinfeng Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study was aimed to investigate whether brain-derived neurotrophic factor (BDNF) can modulate local cerebral inflammation in ischemic stroke. Rats were subjected to ischemia by occluding the right middle cerebral artery (MCAO) for 2 hours. Rats were randomized as control, BDNF, and antibody grou...