In Silico-Based Design and In Vivo Evaluation of an Anthranilic Acid Derivative as a Multitarget Drug in a Diet-Induced Metabolic Syndrome Model

• Main Authors: Héctor González-Álvarez (Author), Astrid Bravo-Jiménez (Author), Matilda Martínez-Arellanes (Author), Gabriela Odette Gamboa-Osorio (Author), Edwin Chávez-Gutiérrez (Author), Lino A. González-Hernández (Author), Karina Gallardo-Ignacio (Author), Osvaldo J. Quintana-Romero (Author), Armando Ariza-Castolo (Author), Christian Guerra-Araiza (Author), Laura Martino-Roaro (Author), Dulce María Meneses-Ruiz (Author), Rodolfo Pinto-Almazán (Author), Marco A. Loza-Mejía (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metabolic syndrome (MetS) is a complex disease that affects almost a quarter of the world's adult population. In MetS, diabetes, obesity, hyperglycemia, high cholesterol, and high blood pressure are the most common disorders. Polypharmacy is the most used strategy for managing conditions relate...