Structure, Activation, and Regulation of NOX2: At the Crossroad between the Innate Immunity and Oxidative Stress-Mediated Pathologies

• Main Authors: Cristina Nocella (Author), Alessandra D'Amico (Author), Vittoria Cammisotto (Author), Simona Bartimoccia (Author), Valentina Castellani (Author), Lorenzo Loffredo (Author), Leonardo Marini (Author), Giulia Ferrara (Author), Matteo Testa (Author), Giulio Motta (Author), Beatrice Benazzi (Author), Fabio Zara (Author), Giacomo Frati (Author), Sebastiano Sciarretta (Author), Pasquale Pignatelli (Author), Francesco Violi (Author), Roberto Carnevale (Author), Smile Group (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) is a multisubunit enzyme complex that participates in the generation of superoxide or hydrogen peroxide (H₂O₂) and plays a key role in several biological functions. Among seven known NOX i...