Are Small Nucleolar RNAs "CRISPRable"? A Report on Box C/D Small Nucleolar RNA Editing in Human Cells

• Main Authors: Julia A. Filippova (Author), Anastasiya M. Matveeva (Author), Evgenii S. Zhuravlev (Author), Evgenia A. Balakhonova (Author), Daria V. Prokhorova (Author), Sergey J. Malanin (Author), Raihan Shah Mahmud (Author), Tatiana V. Grigoryeva (Author), Ksenia S. Anufrieva (Author), Dmitry V. Semenov (Author), Valentin V. Vlassov (Author), Grigory A. Stepanov (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CRISPR technologies are nowadays widely used for targeted knockout of numerous protein-coding genes and for the study of various processes and metabolic pathways in human cells. Most attention in the genome editing field is now focused on the cleavage of protein-coding genes or genes encoding long n...