Therapeutic approach of glutathione/glutathione peroxidase-4 axis modulation in the light of ferroptosis

• Main Authors: Tsvetelin Georgiev (Author), Petya Hadzhibozheva (Author), Yanka Karamalakova (Author), Ekaterina Georgieva (Author), Favas Perinkadakatt (Author), Zlatomir Ilinov (Author), Krasimir Petkov (Author), Julian Ananiev (Author)
• Format: Book
• Published: Pensoft Publishers, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the 21st century beginning, the evidence of a new type of programmed cell death, different from apoptosis, began to accumulate. In 2012, the ferroptosis concept was officially introduced. It refers to a kind of cell death that is associated with iron accumulation in the cell, impaired redox poten...