Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation

• Egile Nagusiak: Richard Mills (Egilea), Hermes Taylor-Weiner (Egilea), Jorge C. Correia (Egilea), Leandro Z. Agudelo (Egilea), Ilary Allodi (Egilea), Christina Kolonelou (Egilea), Vicente Martinez-Redondo (Egilea), Duarte M.S. Ferreira (Egilea), Susanne Nichterwitz (Egilea), Laura H. Comley (Egilea), Vanessa Lundin (Egilea), Eva Hedlund (Egilea), Jorge L. Ruas (Egilea), Ana I. Teixeira (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2018-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: We examined whether skeletal muscle overexpression of PGC-1α1 or PGC-1α4 affected myokine secretion and neuromuscular junction (NMJ) formation. Methods: A microfluidic device was used to model endocrine signaling and NMJ formation between primary mouse myoblast-derived myotubes and embryo...