Amino acid sensing in hypothalamic tanycytes via umami taste receptors

• Main Authors: Greta Lazutkaite (Author), Alice Soldà (Author), Kristina Lossow (Author), Wolfgang Meyerhof (Author), Nicholas Dale (Author)
• 格式: 图书
• 出版: Elsevier, 2017-11-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Objective: Hypothalamic tanycytes are glial cells that line the wall of the third ventricle and contact the cerebrospinal fluid (CSF). While they are known to detect glucose in the CSF we now show that tanycytes also detect amino acids, important nutrients that signal satiety. Methods: Ca2+ imaging...