Forebrain overexpression of CaMKII abolishes cingulate long term depression and reduces mechanical allodynia and thermal hyperalgesia

• Main Authors: Tsien Joe Z (Author), Wang Huimin (Author), Shokat Kevan M (Author), Zhang Chao (Author), Wang Guo-Du (Author), Wei Feng (Author), Liauw Jason (Author), Zhuo Min (Author)
• Format: Book
• Published: SAGE Publishing, 2006-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Activity-dependent synaptic plasticity is known to be important in learning and memory, persistent pain and drug addiction. Glutamate NMDA receptor activation stimulates several protein kinases, which then trigger biochemical cascades that lead to modifications i...