Combination of Lanosterol and Nilvadipine Nanosuspensions Rescues Lens Opacification in Selenite-Induced Cataractic Rats

• Main Authors: Saori Deguchi (Author), Reita Kadowaki (Author), Hiroko Otake (Author), Atsushi Taga (Author), Yosuke Nakazawa (Author), Manju Misra (Author), Naoki Yamamoto (Author), Hiroshi Sasaki (Author), Noriaki Nagai (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It has recently been reported that lanosterol (LAN) plays a preventive role against lens opacification through the reversal of crystalline aggregation. However, the effect of LAN is not sufficient to restore lens transparency. In this study, we designed ophthalmic nanosuspensions (LAN-ONSs and NIL-O...