<i>Quercus acuta</i> Thunb. (Fagaceae) and Its Component, Isoquercitrin, Inhibit HSV-1 Replication by Suppressing Virus-Induced ROS Production and NF-κB Activation

• Main Authors: Buyun Kim (Author), Young Soo Kim (Author), Youn-Hwan Hwang (Author), Hye Jin Yang (Author), Wei Li (Author), Eun-Bin Kwon (Author), Tae In Kim (Author), Younghoon Go (Author), Jang-Gi Choi (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

HSV-1 is a neurotropic virus that replicates lytically during acute infection and establishes latency in peripheral neurons. Currently, the clinically approved compounds for the prevention of HSV-1 infection include acyclovir and penciclovir; however, long-term use of the drug is associated with ser...