Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling

• Main Authors: Lewin Small (Author), Amanda E. Brandon (Author), Benjamin L. Parker (Author), Vinita Deshpande (Author), Azrah F. Samsudeen (Author), Greg M. Kowalski (Author), Jane Reznick (Author), Donna L. Wilks (Author), Elaine Preston (Author), Clinton R. Bruce (Author), David E. James (Author), Nigel Turner (Author), Gregory J. Cooney (Author)
• Format: Book
• Published: Elsevier, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Energy metabolism and insulin action follow a diurnal rhythm. It is therefore important that investigations into dysregulation of these pathways are relevant to the physiology of this diurnal rhythm. Methods: We examined glucose uptake, markers of insulin action, and the phosphorylation o...