Circulating FGF21 and GDF15 as Biomarkers for Screening, Diagnosis, and Severity Assessment of Primary Mitochondrial Disorders in Children

• Hlavní autoři: Yi Li (Autor), Shengrui Li (Autor), Yinfeng Qiu (Autor), Maobin Zhou (Autor), Min Chen (Autor), Yue Hu (Autor), Siqi Hong (Autor), Li Jiang (Autor), Yi Guo (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

BackgroundPrimary mitochondrial disorders (PMDs) are a diagnostic challenge for paediatricians, and identification of reliable and easily measurable biomarkers has become a high priority. This study aimed to investigate the role of serum fibroblast growth factor 21 (FGF21) and growth differentiation...