Association of rs7903146 polymorphism in the TCF7L2 gene with diabetic nephropathy and decreased estimated GFR in an Arab population in southwest Iran

• Main Authors: Ali Karimi Akhormeh (Author), Mehrnoosh Zakerkish (Author), Hamid Yaghooti (Author), Narges Mohammadtaghvaei (Author), Mohammad Taha Jalali (Author), Ramin Tavakoli (Author)
• Format: Book
• Published: Society of Diabetic Nephropathy Prevention, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Transcription factor 7-like 2 (TCF7L2) acts as a downstream effector in the Wnt signaling pathway. It plays important roles in the proliferation and differentiation of islet betacell, insulin secretion and kidney development. Objectives: This study aimed to demonstrate whether rs7903146...