Structure-activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor

Fraxamoside, a macrocyclic secoiridoid glucoside featuring a hydroxytyrosol group, was recently identified as a xanthine oxidase inhibitor (XOI) comparable in potency in vitro to the standard antigout drug allopurinol. However, this activity and its considerably higher value than its derivatives ole...

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Hoofdauteurs: Rosa Maria Vitale (Auteur), Lina Antenucci (Auteur), Margherita Gavagnin (Auteur), Gennaro Raimo (Auteur), Pietro Amodeo (Auteur)
Formaat: Boek
Gepubliceerd in: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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