Structure-activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor

• Главные авторы: Rosa Maria Vitale (Автор), Lina Antenucci (Автор), Margherita Gavagnin (Автор), Gennaro Raimo (Автор), Pietro Amodeo (Автор)
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• Опубликовано: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Предметы: article
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Fraxamoside, a macrocyclic secoiridoid glucoside featuring a hydroxytyrosol group, was recently identified as a xanthine oxidase inhibitor (XOI) comparable in potency in vitro to the standard antigout drug allopurinol. However, this activity and its considerably higher value than its derivatives ole...